The Challenges are similar to Arcade League, however in TimeSplitters 2 and TimeSplitters: Future Perfect they cannot be recreated in Arcade Mode. TimeSplitters 1's Challenge Mode features both unique challenges and missions that can be recreated in Arcade Mode. Many of the challenges have a minigame feel to them and objectives are often more absurd than those in the League.

Completing these challanges not only unlocks more challanges but additional characters and cheats for use in both arcade and single player.